8TBP

HLA-DRB1*15:01 in complex with smith antigen

8TBP の概要

• エントリーDOI: 10.2210/pdb8tbp/pdb
• 分子名称: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1 beta chain, Small nuclear ribonucleoprotein-associated protein N peptide, ... (5 entities in total)
• 機能のキーワード: human leukocyte antigen, hla, major histocompatibility complex, mhc, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 90241.45

構造登録者

Ting, Y.T.,Broury, A.,Ooi, J. (登録日: 2023-06-29, 公開日: 2024-02-21)

• 主引用文献: Eggenhuizen, P.J.,Cheong, R.M.Y.,Lo, C.,Chang, J.,Ng, B.H.,Ting, Y.T.,Monk, J.A.,Loh, K.L.,Broury, A.,Tay, E.S.V.,Shen, C.,Zhong, Y.,Lim, S.,Chung, J.X.,Kandane-Rathnayake, R.,Koelmeyer, R.,Hoi, A.,Chaudhry, A.,Manzanillo, P.,Snelgrove, S.L.,Morand, E.F.,Ooi, J.D.; Smith-specific regulatory T cells halt the progression of lupus nephritis.; Nat Commun, 15:899-899, 2024; PubMed: 38321013; DOI: 10.1038/s41467-024-45056-x

実験手法

X-RAY DIFFRACTION (3.1262111426 Å)