8T99

Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with Scyllo-L-1,4-[PP]2-(2,3)IP2, Mg, and Fluoride ion

8T99 の概要

• エントリーDOI: 10.2210/pdb8t99/pdb
• 分子名称: Diphosphoinositol polyphosphate phosphohydrolase 1, (1R,2S,3S,4R,5S,6S)-2,3-dihydroxy-5,6-bis(phosphonooxy)cyclohexane-1,4-diyl bis[trihydrogen (diphosphate)], MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: inositol phosphate, inositol, phosphatase, nut3, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17938.22

構造登録者

Zong, G.,Wang, H.,Shears, S.B. (登録日: 2023-06-23, 公開日: 2023-11-15, 最終更新日: 2024-02-14)

• 主引用文献: Zong, G.,Desfougeres, Y.,Portela-Torres, P.,Kwon, Y.U.,Saiardi, A.,Shears, S.B.,Wang, H.; Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus.; Embo J., 43:462-480, 2024; PubMed: 38216735; DOI: 10.1038/s44318-023-00005-0

実験手法

X-RAY DIFFRACTION (1.5 Å)