8T7E
Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma
Summary for 8T7E
Entry DOI | 10.2210/pdb8t7e/pdb |
Related | 8G5I 8G5J 8G5K 8G5L 8G5M 8G5N 8G5O 8G5P |
EMDB information | 41091 |
Descriptor | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, Mismatched Primer DNA, ... (4 entities in total) |
Functional Keywords | mitochondrial dna polymerase, dna proofreading, backtracking, mismatch repair, replication, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 263815.80 |
Authors | Nayak, A.R.,Buchel, G.,Herbine, K.H.,Sarfallah, A.,Sokolova, V.O.,Zamudio-Ochoa, A.,Temiakov, D. (deposition date: 2023-06-20, release date: 2024-01-10) |
Primary citation | Buchel, G.,Nayak, A.R.,Herbine, K.,Sarfallah, A.,Sokolova, V.O.,Zamudio-Ochoa, A.,Temiakov, D. Structural basis for DNA proofreading. Nat Commun, 14:8501-8501, 2023 Cited by PubMed: 38151585DOI: 10.1038/s41467-023-44198-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
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