8T3M
TRPV1 in nanodisc bound with 3 LPA molecules
Summary for 8T3M
Entry DOI | 10.2210/pdb8t3m/pdb |
EMDB information | 41006 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, [(2~{R})-2-hexadecanoyloxy-3-[oxidanyl-[(2~{S},3~{S},5~{R},6~{S})-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] hexadecanoate, SODIUM ION, ... (4 entities in total) |
Functional Keywords | trpv1, lysophosphatidic acid, membrane protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 4 |
Total formula weight | 294069.71 |
Authors | Arnold, W.R.,Julius, D.,Cheng, Y. (deposition date: 2023-06-07, release date: 2024-05-08, Last modification date: 2024-10-02) |
Primary citation | Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y. Structural basis of TRPV1 modulation by endogenous bioactive lipids. Nat.Struct.Mol.Biol., 31:1377-1385, 2024 Cited by PubMed: 38698206DOI: 10.1038/s41594-024-01299-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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