8T10

TRPV1 in nanodisc bound with two LPA molecules in opposite monomers

8T10 の概要

• エントリーDOI: 10.2210/pdb8t10/pdb
• EMDBエントリー: 40951
• 分子名称: Transient receptor potential cation channel subfamily V member 1, (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: trpv1 in nanodisc bound with two lpa molecules in opposite monomers, membrane protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 373161.80

構造登録者

Arnold, W.R.,Julius, D.,Cheng, Y. (登録日: 2023-06-01, 公開日: 2024-05-08, 最終更新日: 2024-05-15)

• 主引用文献: Arnold, W.R.,Mancino, A.,Moss 3rd, F.R.,Frost, A.,Julius, D.,Cheng, Y.; Structural basis of TRPV1 modulation by endogenous bioactive lipids.; Nat.Struct.Mol.Biol., 2024; PubMed: 38698206; DOI: 10.1038/s41594-024-01299-2

実験手法

ELECTRON MICROSCOPY (3.7 Å)