8SXW

X-ray crystal structure of UDP- 2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase from Thermus thermophilus strain HB27, D98N mutation, apo structure at pH 6

Summary for 8SXW

Entry DOI	10.2210/pdb8sxw/pdb
Related	8SXV
Descriptor	UDP-2,3-diacetamido-2,3-dideoxy-glucuronic acid-2-epimerase, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	lipopolysaccharide, o-antigen, 2-epimerase, isomerase
Biological source	Thermus thermophilus HB27
Total number of polymer chains	4
Total formula weight	164566.48
Authors	Kroft, C.W.,Thoden, J.B.,Holden, H.M. (deposition date: 2023-05-24, release date: 2023-09-13, Last modification date: 2023-10-18)
Primary citation	Thoden, J.B.,McKnight, J.O.,Kroft, C.W.,Jast, J.D.T.,Holden, H.M. Structural analysis of a bacterial UDP-sugar 2-epimerase reveals the active site architecture before and after catalysis. J.Biol.Chem., 299:105200-105200, 2023 Cited by PubMed: 37660908 DOI: 10.1016/j.jbc.2023.105200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation