8SPO

Tetramerized activation of MapSPARTA bound with NAD+

Summary for 8SPO

Entry DOI	10.2210/pdb8spo/pdb
EMDB information	40680
Descriptor	TIR domain-containing protein, Piwi domain-containing protein, guide RNA, ... (6 entities in total)
Functional Keywords	short pago, sparta, prokaryotic argonaute, tir domain, nad+, immune system, oligomerization
Biological source	Maribacter polysiphoniae More
Total number of polymer chains	16
Total formula weight	503655.10
Authors	Shen, Z.F.,Yang, X.Y.,Fu, T.M. (deposition date: 2023-05-03, release date: 2023-08-23, Last modification date: 2023-09-20)
Primary citation	Shen, Z.,Yang, X.Y.,Xia, S.,Huang, W.,Taylor, D.J.,Nakanishi, K.,Fu, T.M. Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621:154-161, 2023 Cited by PubMed: 37494956 DOI: 10.1038/s41586-023-06456-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.98 Å)

Structure validation