8SMK

hPAD4 bound to Activating Fab hA362

Summary for 8SMK

• Entry DOI: 10.2210/pdb8smk/pdb
• EMDB information: 40589
• Descriptor: Protein-arginine deiminase type-4, Activating Fab 362 heavy chain, Activating Fab 362 light chain, ... (4 entities in total)
• Functional Keywords: complex, enzyme, inflammation, calcium binding, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 251662.95

Authors

Maker, A.,Verba, K.A. (deposition date: 2023-04-26, release date: 2024-03-06, Last modification date: 2024-06-12)

• Primary citation: Zhou, X.,Kong, S.,Maker, A.,Remesh, S.G.,Leung, K.K.,Verba, K.A.,Wells, J.A.; Antibody discovery identifies regulatory mechanisms of protein arginine deiminase 4.; Nat.Chem.Biol., 20:742-750, 2024; PubMed: 38308046; DOI: 10.1038/s41589-023-01535-8

Experimental method

ELECTRON MICROSCOPY (3.5 Å)