8SMD

Structure of Clostridium botulinum prophage Tad1 in complex with 1''-3' gcADPR

Summary for 8SMD

• Entry DOI: 10.2210/pdb8smd/pdb
• Descriptor: ABC transporter ATPase, (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione (3 entities in total)
• Functional Keywords: gcadpr, thoeris, anti-phage, unknown function
• Biological source: Clostridium botulinum
• Total number of polymer chains: 2
• Total formula weight: 29744.76

Authors

Lu, A.,Yirmiya, E.,Leavitt, A.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Amitai, G.,Sorek, R.,Kranzusch, P.J. (deposition date: 2023-04-26, release date: 2023-11-22, Last modification date: 2024-01-24)

• Primary citation: Yirmiya, E.,Leavitt, A.,Lu, A.,Ragucci, A.E.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Kranzusch, P.J.,Amitai, G.,Sorek, R.; Phages overcome bacterial immunity via diverse anti-defence proteins.; Nature, 625:352-359, 2024; PubMed: 37992756; DOI: 10.1038/s41586-023-06869-w

Experimental method

X-RAY DIFFRACTION (2.1 Å)