8SMD

Structure of Clostridium botulinum prophage Tad1 in complex with 1''-3' gcADPR

8SMD の概要

• エントリーDOI: 10.2210/pdb8smd/pdb
• 分子名称: ABC transporter ATPase, (2R,3R,3aS,5S,6R,7S,8R,11R,13S,15aR)-2-(6-amino-9H-purin-9-yl)-3,6,7,11,13-pentahydroxyoctahydro-2H,5H,11H,13H-5,8-epoxy-11lambda~5~,13lambda~5~-furo[2,3-g][1,3,5,9,2,4]tetraoxadiphosphacyclotetradecine-11,13-dione (3 entities in total)
• 機能のキーワード: gcadpr, thoeris, anti-phage, unknown function
• 由来する生物種: Clostridium botulinum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29744.76

構造登録者

Lu, A.,Yirmiya, E.,Leavitt, A.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Amitai, G.,Sorek, R.,Kranzusch, P.J. (登録日: 2023-04-26, 公開日: 2023-11-22, 最終更新日: 2024-01-24)

• 主引用文献: Yirmiya, E.,Leavitt, A.,Lu, A.,Ragucci, A.E.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Kranzusch, P.J.,Amitai, G.,Sorek, R.; Phages overcome bacterial immunity via diverse anti-defence proteins.; Nature, 625:352-359, 2024; PubMed: 37992756; DOI: 10.1038/s41586-023-06869-w

実験手法

X-RAY DIFFRACTION (2.1 Å)