8SLW
Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-4
Summary for 8SLW
Entry DOI | 10.2210/pdb8slw/pdb |
EMDB information | 40574 40575 40576 40577 40578 40579 40580 40581 40592 |
Descriptor | Transient receptor potential cation channel subfamily M member 5, CALCIUM ION (2 entities in total) |
Functional Keywords | ion channel, transient receptor potential, trp, transient receptor potential melastatin 5, trpm5, membrane protein, transport protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 4 |
Total formula weight | 529727.50 |
Authors | Karuppan, S.,Schrag, L.G.,Jara-Oseguera, A.,Zubcevic, L. (deposition date: 2023-04-24, release date: 2024-07-03, Last modification date: 2024-07-10) |
Primary citation | Karuppan, S.,Schrag, L.G.,Pastrano, C.M.,Jara-Oseguera, A.,Zubcevic, L. Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. Proc.Natl.Acad.Sci.USA, 121:e2403333121-e2403333121, 2024 Cited by PubMed: 38923985DOI: 10.1073/pnas.2403333121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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