8SLW

Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-4

8SLW の概要

• エントリーDOI: 10.2210/pdb8slw/pdb
• EMDBエントリー: 40574 40575 40576 40577 40578 40579 40580 40581 40592
• 分子名称: Transient receptor potential cation channel subfamily M member 5, CALCIUM ION (2 entities in total)
• 機能のキーワード: ion channel, transient receptor potential, trp, transient receptor potential melastatin 5, trpm5, membrane protein, transport protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 529727.50

構造登録者

Karuppan, S.,Schrag, L.G.,Jara-Oseguera, A.,Zubcevic, L. (登録日: 2023-04-24, 公開日: 2024-07-03, 最終更新日: 2024-07-10)

• 主引用文献: Karuppan, S.,Schrag, L.G.,Pastrano, C.M.,Jara-Oseguera, A.,Zubcevic, L.; Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.; Proc.Natl.Acad.Sci.USA, 121:e2403333121-e2403333121, 2024; PubMed: 38923985; DOI: 10.1073/pnas.2403333121

実験手法

ELECTRON MICROSCOPY (4.2 Å)