8SLP

Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-2

Summary for 8SLP

Entry DOI	10.2210/pdb8slp/pdb
EMDB information	40574 40575 40576 40577 40578 40579 40580 40581 40595
Descriptor	Transient receptor potential cation channel subfamily M member 5, CALCIUM ION (2 entities in total)
Functional Keywords	ion channel, transient receptor potential, trp, transient receptor potential melastatin 5, trpm5, membrane protein, transport protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	529727.50
Authors	Karuppan, S.,Schrag, L.G.,Jara-Oseguera, A.,Zubcevic, L. (deposition date: 2023-04-24, release date: 2024-07-03, Last modification date: 2024-07-10)
Primary citation	Karuppan, S.,Schrag, L.G.,Pastrano, C.M.,Jara-Oseguera, A.,Zubcevic, L. Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel. Proc.Natl.Acad.Sci.USA, 121:e2403333121-e2403333121, 2024 Cited by PubMed: 38923985 DOI: 10.1073/pnas.2403333121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation