8SJK
Pembrolizumab Caffeine crystal
Summary for 8SJK
Entry DOI | 10.2210/pdb8sjk/pdb |
Related PRD ID | PRD_900003 |
Descriptor | ANTIBODY LIGHT CHAIN, ANTIBODY HEAVY CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | cancer, antibody, subclasses, igg4, melanoma, nsclc, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 75130.49 |
Authors | Larpent, P.,Codan, L.,Bothe, J.R.,Stueber, D.,Reichert, P.,Fischmann, T.,Su, Y.,Pabit, S.,Gupta, S.,Iuzzolino, L.,Cote, A. (deposition date: 2023-04-18, release date: 2024-04-24, Last modification date: 2024-08-21) |
Primary citation | Larpent, P.,Codan, L.,Bothe, J.R.,Iuzzolino, L.,Pabit, S.,Gupta, S.,Fischmann, T.,Su, Y.,Reichert, P.,Stueber, D.,Cote, A. Small-Angle X-ray Scattering as a Powerful Tool for Phase and Crystallinity Assessment of Monoclonal Antibody Crystallites in Support of Batch Crystallization. Mol Pharm., 21:4024-4037, 2024 Cited by PubMed: 38958508DOI: 10.1021/acs.molpharmaceut.4c00418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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