8SEZ
Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD)
Summary for 8SEZ
Entry DOI | 10.2210/pdb8sez/pdb |
EMDB information | 40422 40423 40424 40425 40426 40427 40428 40429 40430 40431 40432 40433 40434 40435 |
Descriptor | Ryanodine receptor 1, ADENINE, ZINC ION (3 entities in total) |
Functional Keywords | calcium ion channel, skeletal muscle, nucleotide, homotetramer, transport protein |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 4 |
Total formula weight | 2264436.64 |
Authors | Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Van Petegem, F.,Subramaniam, S. (deposition date: 2023-04-10, release date: 2023-05-24, Last modification date: 2023-07-19) |
Primary citation | Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Alvarado, F.J.,Van Petegem, F.,Subramaniam, S. Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31:790-800.e4, 2023 Cited by PubMed: 37192614DOI: 10.1016/j.str.2023.04.009 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.54 Å) |
Structure validation
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