8SCU
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State)
Summary for 8SCU
Entry DOI | 10.2210/pdb8scu/pdb |
Descriptor | DNA polymerase I, NP-extended DNA primer, DNA template, ... (8 entities in total) |
Functional Keywords | dna polymerase, np-dna, origin of life, time-resolved crystallography, replication-dna complex, replication/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 6 |
Total formula weight | 147638.32 |
Authors | Fang, Z.,Lelyveld, V.S.,Szostak, J.W. (deposition date: 2023-04-05, release date: 2023-10-25, Last modification date: 2023-11-08) |
Primary citation | Lelyveld, V.S.,Fang, Z.,Szostak, J.W. Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382:423-429, 2023 Cited by PubMed: 37883544DOI: 10.1126/science.adh5339 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
Download full validation report