8SCG
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 0h (Ground State)
Summary for 8SCG
| Entry DOI | 10.2210/pdb8scg/pdb |
| Descriptor | DNA polymerase I, 3'-Amino DNA Primer, DNA Tempelate, ... (7 entities in total) |
| Functional Keywords | dna polymerase, np-dna, origin of life, time-resolved crystallography, dna binding protein, replication-dna complex, replication/dna |
| Biological source | Geobacillus stearothermophilus More |
| Total number of polymer chains | 6 |
| Total formula weight | 146979.07 |
| Authors | Fang, Z.,Lelyveld, V.S.,Szostak, J.W. (deposition date: 2023-04-05, release date: 2023-10-25, Last modification date: 2023-11-08) |
| Primary citation | Lelyveld, V.S.,Fang, Z.,Szostak, J.W. Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity. Science, 382:423-429, 2023 Cited by PubMed: 37883544DOI: 10.1126/science.adh5339 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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