8SC1

Human OCT1 (Apo) in inward-open conformation

Summary for 8SC1

Entry DOI	10.2210/pdb8sc1/pdb
EMDB information	40334
Descriptor	Solute carrier family 22 member 1 (1 entity in total)
Functional Keywords	membrane protein, mfs, drug transporter, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	61200.66
Authors	Zeng, Y.C.,Sobti, M.,Stewart, A.G. (deposition date: 2023-04-04, release date: 2023-10-18, Last modification date: 2023-10-25)
Primary citation	Zeng, Y.C.,Sobti, M.,Quinn, A.,Smith, N.J.,Brown, S.H.J.,Vandenberg, J.I.,Ryan, R.M.,O'Mara, M.L.,Stewart, A.G. Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. Nat Commun, 14:6374-6374, 2023 Cited by PubMed: 37821493 DOI: 10.1038/s41467-023-42086-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.92 Å)

Structure validation