8SAS

CryoEM structure of DH270.5-CH848.10.17

8SAS の概要

• エントリーDOI: 10.2210/pdb8sas/pdb
• EMDBエントリー: 40273 40274 40275 40277 40278 40279 40280 40281 40282 40283 40284 40285 40286 40287 40288 40289 40290 40291
• 分子名称: CH848.10.17 gp120, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• 機能のキーワード: hiv-1, antibody, dh270.5, ch848.10.17, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: HIV-1 06TG.HT008; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 288607.28

構造登録者

Henderson, R.,Zhou, Y.,Stalls, V.,Bartesaghi, B.,Acharya, P. (登録日: 2023-04-01, 公開日: 2023-04-19, 最終更新日: 2023-05-31)

• 主引用文献: Henderson, R.,Zhou, Y.,Stalls, V.,Wiehe, K.,Saunders, K.O.,Wagh, K.,Anasti, K.,Barr, M.,Parks, R.,Alam, S.M.,Korber, B.,Haynes, B.F.,Bartesaghi, A.,Acharya, P.; Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.; Nat Commun, 14:2782-2782, 2023; PubMed: 37188681; DOI: 10.1038/s41467-023-38108-1

実験手法

ELECTRON MICROSCOPY (4 Å)