8S9L

Structure of monomeric FAM111A SPD V347D Mutant

Summary for 8S9L

• Entry DOI: 10.2210/pdb8s9l/pdb
• Descriptor: Serine protease FAM111A, SULFATE ION (3 entities in total)
• Functional Keywords: protease, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 61866.19

Authors

Palani, S.,Alvey, J.A.,Cong, A.T.Q.,Schellenberg, M.J.,Machida, Y. (deposition date: 2023-03-29, release date: 2024-03-20)

• Primary citation: Palani, S.,Machida, Y.,Alvey, J.R.,Mishra, V.,Welter, A.L.,Cui, G.,Bragantini, B.,Botuyan, M.V.,Cong, A.T.Q.,Mer, G.,Schellenberg, M.J.,Machida, Y.J.; Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes.; Nat Commun, 15:2064-2064, 2024; PubMed: 38453899; DOI: 10.1038/s41467-024-46207-w

Experimental method

X-RAY DIFFRACTION (1.85 Å)