8S9C
Cryo-EM structure of Nav1.7 with CBZ
Summary for 8S9C
Entry DOI | 10.2210/pdb8s9c/pdb |
EMDB information | 40239 |
Descriptor | Sodium channel protein type 9 subunit alpha, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Sodium channel subunit beta-1, ... (11 entities in total) |
Functional Keywords | cryo-em, sodium channel, vgsc, nav1.7, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 290878.24 |
Authors | |
Primary citation | Wu, Q.,Huang, J.,Fan, X.,Wang, K.,Jin, X.,Huang, G.,Li, J.,Pan, X.,Yan, N. Structural mapping of Na v 1.7 antagonists. Nat Commun, 14:3224-3224, 2023 Cited by PubMed: 37270609DOI: 10.1038/s41467-023-38942-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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