8S7Z

Urethanase umg-sp1 without inhibitor or substrate displays flexible active site loops

Summary for 8S7Z

Entry DOI	10.2210/pdb8s7z/pdb
Descriptor	Urethanase umg-sp1 (2 entities in total)
Functional Keywords	urethanase, amidase, amidase signature protein superfamily, catalytic triad, hydrolase
Biological source	metagenome
Total number of polymer chains	4
Total formula weight	186105.28
Authors	Palm, G.J.,Graf, L.G.,Berndt, L.,Lammers, M. (deposition date: 2024-03-05, release date: 2024-07-24, Last modification date: 2024-10-09)
Primary citation	Bayer, T.,Palm, G.J.,Berndt, L.,Meinert, H.,Branson, Y.,Schmidt, L.,Cziegler, C.,Somvilla, I.,Zurr, C.,Graf, L.G.,Janke, U.,Badenhorst, C.P.S.,Konig, S.,Delcea, M.,Garscha, U.,Wei, R.,Lammers, M.,Bornscheuer, U.T. Structural Elucidation of a Metagenomic Urethanase and Its Engineering Towards Enhanced Hydrolysis Profiles. Angew.Chem.Int.Ed.Engl., 63:e202404492-e202404492, 2024 Cited by PubMed: 38948941 DOI: 10.1002/anie.202404492 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation