8S7K

M. tuberculosis gyrase holocomplex with 150 bp DNA and gepotidacin

Summary for 8S7K

• Entry DOI: 10.2210/pdb8s7k/pdb
• EMDB information: 19777
• Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, DNA (5'-D(*AP*GP*TP*AP*TP*TP*AP*CP*CP*CP*CP*TP*TP*CP*CP*GP*GP*A)-3'), ... (6 entities in total)
• Functional Keywords: mycobacterium tuberculosis, dna gyrase, novel bacterial topoisomerase ii inhibitors, antibiotic resistance, structure-activity relation, dna binding protein
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 6
• Total formula weight: 426570.24

Authors

Mechaly, A.,Gubellini, F.,Yab, E.,Willand, N.,Petrella, S. (deposition date: 2024-03-01, release date: 2025-10-08)

• Primary citation: Gedeon, A.,Yab, E.,Dinut, A.,Sadowski, E.,Capton, E.,Dreneau, A.,Gioia, B.,Piveteau, C.,Djaout, K.,Lecat, E.,Wehenkel, A.M.,Gubellini, F.,Mechaly, A.,Alzari, P.M.,Deprez, B.,Baulard, A.,Aubry, A.,Willand, N.,Petrella, S.; M. tuberculosis gyrase holocomplex with 150 bp DNA and gepotidacin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)