8S67

Galectin-3 with a small molecule inhibitor

Summary for 8S67

Entry DOI	10.2210/pdb8s67/pdb
Descriptor	Galectin-3, (2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(1-~{tert}-butyl-1,2,3-triazol-4-yl)methyl]-2-(hydroxymethyl)-5-methoxy-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-3-ol, THIOCYANATE ION, ... (4 entities in total)
Functional Keywords	inhibitor, sugar binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16255.61
Authors	Mac Sweeney, A.,Sager, C. (deposition date: 2024-02-26, release date: 2025-03-12)
Primary citation	Remen, L.,Zumbrunn, C.,Sager, C.P.,Grisostomi, C.,Mac Sweeney, A.,Gatfield, J.,Huehn, E.,Vercauteren, E.,Fournier, E.,Schmidt, G.,Davenport, R.,Iglarz, M.,Nayler, O.,Bolli, M.H. Galectin-3 with a small molecule inhibitor To Be Published,
Experimental method	X-RAY DIFFRACTION (1.097 Å)

Structure validation