8S5N
RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt
Summary for 8S5N
Entry DOI | 10.2210/pdb8s5n/pdb |
EMDB information | 19743 |
Descriptor | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, ... (25 entities in total) |
Functional Keywords | rna polymerase ii, promoter escape, de novo transcription, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 23 |
Total formula weight | 923621.31 |
Authors | Zhan, Y.,Grabbe, F.,Oberbeckmann, E.,Dienemann, C.,Cramer, P. (deposition date: 2024-02-24, release date: 2024-04-10, Last modification date: 2024-05-15) |
Primary citation | Zhan, Y.,Grabbe, F.,Oberbeckmann, E.,Dienemann, C.,Cramer, P. Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84:1699-1710.e6, 2024 Cited by PubMed: 38604172DOI: 10.1016/j.molcel.2024.03.016 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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