8S1B

c-KIT kinase domain in complex with IDRX-42 via soaking

Summary for 8S1B

• Entry DOI: 10.2210/pdb8s1b/pdb
• Descriptor: Mast/stem cell growth factor receptor Kit, ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: stem cell factor receptor, gist, cancer, inhibitor, resistances, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 76494.23

Authors

Teuber, A.,Mueller, M.P.,Rauh, D. (deposition date: 2024-02-15, release date: 2025-09-03)

• Primary citation: Teuber, A.,Niggenaber, J.,Kleinboelting, S.B.,Landel, I.,Warmuth, J.,Busick, D.,Mueller, M.P.,Bauer, S.,Rauh, D.; c-KIT kinase domain in complex with IDRX-42 via soaking; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)