8S1B

c-KIT kinase domain in complex with IDRX-42 via soaking

8S1B の概要

• エントリーDOI: 10.2210/pdb8s1b/pdb
• 分子名称: Mast/stem cell growth factor receptor Kit, ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: stem cell factor receptor, gist, cancer, inhibitor, resistances, transferase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76494.23

構造登録者

Teuber, A.,Mueller, M.P.,Rauh, D. (登録日: 2024-02-15, 公開日: 2025-09-03)

• 主引用文献: Teuber, A.,Niggenaber, J.,Kleinboelting, S.B.,Landel, I.,Warmuth, J.,Busick, D.,Mueller, M.P.,Bauer, S.,Rauh, D.; c-KIT kinase domain in complex with IDRX-42 via soaking; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)