8S0C
H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex
Summary for 8S0C
Entry DOI | 10.2210/pdb8s0c/pdb |
EMDB information | 19618 19619 19621 19622 19623 19624 19625 |
Descriptor | Origin recognition complex subunit 1, DNA (26-mer), Origin recognition complex subunit 2, ... (9 entities in total) |
Functional Keywords | aaa+ atpase, dna helicase, replication |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 363860.03 |
Authors | Greiwe, J.F.,Weissmann, F.,Diffley, J.F.X.,Costa, A. (deposition date: 2024-02-13, release date: 2024-10-02) |
Primary citation | Weissmann, F.,Greiwe, J.F.,Puehringer, T.,Eastwood, E.L.,Couves, E.C.,Miller, T.C.R.,Diffley, J.F.X.,Costa, A. MCM Double Hexamer Loading Visualised with Human Proteins Nature, 2024 |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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