8RZX

Solution structure of a parallel stranded G-quadruplex formed in ORAI1 promoter

Summary for 8RZX

• Entry DOI: 10.2210/pdb8rzx/pdb
• Descriptor: DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*GP*GP*CP*AP*CP*AP*GP*GP*TP*GP*GP*GP*CP*GP*GP*GP*G)-3') (1 entity in total)
• Functional Keywords: g-quadruplex, parallel topology, orai1, long loop, dna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 7613.86

Authors

Jana, J.,Weisz, K. (deposition date: 2024-02-13, release date: 2024-08-21)

• Primary citation: Chatterjee, O.,Jana, J.,Panda, S.,Dutta, A.,Sharma, A.,Saurav, S.,Motiani, R.K.,Weisz, K.,Chatterjee, S.; Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer; Cell Calcium, 2024; DOI: 10.1016/j.ceca.2024.102944

Experimental method