8RV7
SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 4
This is a non-PDB format compatible entry.
Summary for 8RV7
Entry DOI | 10.2210/pdb8rv7/pdb |
Descriptor | 2'-O-methyltransferase nsp16, Non-structural protein 10, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total) |
Functional Keywords | nsp16, nsp10, 2'-o-methyltransferase, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 2 |
Total formula weight | 49579.46 |
Authors | Kalnins, G. (deposition date: 2024-01-31, release date: 2024-02-14, Last modification date: 2024-10-02) |
Primary citation | Kalnins, G.,Rudusa, L.,Bula, A.,Zelencova-Gopejenko, D.,Bobileva, O.,Sisovs, M.,Tars, K.,Jirgensons, A.,Jaudzems, K.,Bobrovs, R. Structural basis for inhibition of the SARS-CoV-2 nsp16 by substrate-based dual site inhibitors. Chemmedchem, :e202400618-e202400618, 2024 Cited by PubMed: 39258386DOI: 10.1002/cmdc.202400618 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report