8RSJ

Crystal structure of Methanobrevibacter oralis macrodomain in complex with ADPr in open conformation

Summary for 8RSJ

Entry DOI	10.2210/pdb8rsj/pdb
Descriptor	O-acetyl-ADP-ribose deacetylase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate, ... (5 entities in total)
Functional Keywords	adp-ribosylation, adp-ribose, adp-ribosylhydrolase, lipoylation, metalloenzyme, hydrolase
Biological source	Methanobrevibacter oralis
Total number of polymer chains	2
Total formula weight	60689.13
Authors	Ariza, A. (deposition date: 2024-01-24, release date: 2024-09-25, Last modification date: 2024-10-02)
Primary citation	Ariza, A.,Liu, Q.,Cowieson, N.,Ahel, I.,Filippov, D.V.,Rack, J.G.M. Evolutionary and molecular basis of ADP-ribosylation reversal by zinc-dependent macrodomains. J.Biol.Chem., :107770-107770, 2024 Cited by PubMed: 39270823 DOI: 10.1016/j.jbc.2024.107770 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation