8RRT

Structure of rabbit RyR1 reconstituted into lipid liposomes in open state in complex with FKBP and Nb9657

This is a non-PDB format compatible entry.

Summary for 8RRT

• Entry DOI: 10.2210/pdb8rrt/pdb
• EMDB information: 19464
• Descriptor: Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Nanobody 9657, ... (7 entities in total)
• Functional Keywords: ion channel, ca2+, tetramer, transport protein
• Biological source: Vicugna pacos; More
• Total number of polymer chains: 12
• Total formula weight: 2370125.64

Authors

Li, C.,Efremov, R.G. (deposition date: 2024-01-23, release date: 2024-10-09)

• Primary citation: Li, C.,Willegems, K.,Uchanski, T.,Pardon, E.,Steyaert, J.,Efremov, R.G.; Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM.; J.Biol.Chem., :107734-107734, 2024; PubMed: 39233227; DOI: 10.1016/j.jbc.2024.107734

Experimental method

ELECTRON MICROSCOPY (4.6 Å)