8RQ3

Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)

8RQ3 の概要

• エントリーDOI: 10.2210/pdb8rq3/pdb
• EMDBエントリー: 19431
• 分子名称: ATP-binding cassette sub-family C member 2 (1 entity in total)
• 機能のキーワード: multidrug resistance-associated protein 2 (rmrp2) in an autoinhibited state (nucleotide-free), transport protein
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 173571.58

構造登録者

Mazza, T.,Beis, K. (登録日: 2024-01-17, 公開日: 2024-02-14, 最終更新日: 2024-03-13)

• 主引用文献: Mazza, T.,Roumeliotis, T.I.,Garitta, E.,Drew, D.,Rashid, S.T.,Indiveri, C.,Choudhary, J.S.,Linton, K.J.,Beis, K.; Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.; Nat Commun, 15:1983-1983, 2024; PubMed: 38438394; DOI: 10.1038/s41467-024-46392-8

実験手法

ELECTRON MICROSCOPY (3.21 Å)