8RPK

AMP-forming Acetyl-CoA synthetase from Chloroflexota bacterium without bound ligand

8RPK の概要

• エントリーDOI: 10.2210/pdb8rpk/pdb
• 分子名称: Acetate--CoA ligase, MAGNESIUM ION, POTASSIUM ION, ... (4 entities in total)
• 機能のキーワード: acsa, coa, phospho histidine, ligase
• 由来する生物種: Chloroflexota bacterium
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 296602.38

構造登録者

Striska, K.,Palm, G.J.,Lammers, M. (登録日: 2024-01-16, 公開日: 2024-06-19, 最終更新日: 2024-07-31)

• 主引用文献: Qin, C.,Graf, L.G.,Striska, K.,Janetzky, M.,Geist, N.,Specht, R.,Schulze, S.,Palm, G.J.,Girbardt, B.,Dorre, B.,Berndt, L.,Kemnitz, S.,Doerr, M.,Bornscheuer, U.T.,Delcea, M.,Lammers, M.; Acetyl-CoA synthetase activity is enzymatically regulated by lysine acetylation using acetyl-CoA or acetyl-phosphate as donor molecule.; Nat Commun, 15:6002-6002, 2024; PubMed: 39019872; DOI: 10.1038/s41467-024-49952-0

実験手法

X-RAY DIFFRACTION (2.615 Å)