8RPE

Crystal structure of the SMA:VH1 Complex at 1.2 A resolution

8RPE の概要

• エントリーDOI: 10.2210/pdb8rpe/pdb
• 分子名称: VH1, SMA, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: stabilisation of amyloidogenic light chains; therapeutics development, immune system
• 由来する生物種: Lama; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27474.24

構造登録者

Maerivoet, A.,Crabbe, T.,Antonyuk, S.V.,Madine, J. (登録日: 2024-01-15, 公開日: 2025-01-29)

• 主引用文献: Maerivoet, A.,Galmiche, S.,Scott-Tucker, A.,Crabbe, T.,Antonyuk, S.,Madine, J.; Stabilisation of amyloidogenic light chains by displacing native dimer binding interface with the variable heavy domain have potential for therapeutics development; To be published,

実験手法

X-RAY DIFFRACTION (1.2 Å)