8RN8

Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S))

8RN8 の概要

• エントリーDOI: 10.2210/pdb8rn8/pdb
• EMDBエントリー: 19390
• 分子名称: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (4 entities in total)
• 機能のキーワード: viral polymerase, viral protein
• 由来する生物種: Influenza B virus (B/Memphis/13/2003); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 517194.74

構造登録者

Arragain, B.,Cusack, S. (登録日: 2024-01-09, 公開日: 2024-09-11)

• 主引用文献: Arragain, B.,Krischuns, T.,Pelosse, M.,Drncova, P.,Blackledge, M.,Naffakh, N.,Cusack, S.; Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.; Nat Commun, 15:6910-6910, 2024; PubMed: 39160148; DOI: 10.1038/s41467-024-51007-3

実験手法

ELECTRON MICROSCOPY (2.92 Å)