8RII
Structure of E166A BlaC from Mycobacterium tuberculosis at pH 6.5
Summary for 8RII
Entry DOI | 10.2210/pdb8rii/pdb |
Descriptor | Beta-lactamase (2 entities in total) |
Functional Keywords | beta-lactamase, hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 28214.69 |
Authors | Sun, J.,Bruenle, S.,Ubbink, M. (deposition date: 2023-12-18, release date: 2024-08-28, Last modification date: 2024-10-09) |
Primary citation | Sun, J.,Boyle, A.L.,Brunle, S.,Ubbink, M. A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC. Int.J.Biol.Macromol., 278:134665-134665, 2024 Cited by PubMed: 39134195DOI: 10.1016/j.ijbiomac.2024.134665 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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