8RH6
Crystal structure of HLA-A*11:01 in complex with SVLNDILSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
Summary for 8RH6
Entry DOI | 10.2210/pdb8rh6/pdb |
Descriptor | HLA class I histocompatibility antigen, Beta-2-microglobulin, Spike protein S2', ... (5 entities in total) |
Functional Keywords | human leukocyte antigen, major histocompatibility complex, hla-a11, hla-a*11:01, sars-cov-2, spike, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 9 |
Total formula weight | 162154.39 |
Authors | Ahn, Y.M.,Maddumage, J.C.,Szeto, C.,Gras, S. (deposition date: 2023-12-15, release date: 2024-05-15, Last modification date: 2024-05-22) |
Primary citation | Ahn, Y.M.,Maddumage, J.C.,Grant, E.J.,Chatzileontiadou, D.S.M.,Perera, W.W.J.G.,Baker, B.M.,Szeto, C.,Gras, S. The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific. Curr Res Struct Biol, 7:100148-100148, 2024 Cited by PubMed: 38742159DOI: 10.1016/j.crstbi.2024.100148 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.32 Å) |
Structure validation
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