8RFZ
Structure of E166A BlaC from Mycobacterium tuberculosis at pH 4.5
Summary for 8RFZ
Entry DOI | 10.2210/pdb8rfz/pdb |
Descriptor | Beta-lactamase, SULFATE ION (3 entities in total) |
Functional Keywords | beta-lactamase from mycobacterium tuberculosis and encoded by blac gene, hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 28406.81 |
Authors | |
Primary citation | Sun, J.,Boyle, A.L.,Brunle, S.,Ubbink, M. A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC. Int.J.Biol.Macromol., 278:134665-134665, 2024 Cited by PubMed: 39134195DOI: 10.1016/j.ijbiomac.2024.134665 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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