8RFN

Human NOQ1 enzyme in its holo form by serial crystallography

Summary for 8RFN

• Entry DOI: 10.2210/pdb8rfn/pdb
• Related: 8RFM
• Descriptor: NAD(P)H dehydrogenase [quinone] 1, FLAVIN-ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: human nqo1, oxidoreductase, flavoenzyme, flavoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 127010.95

Authors

Martin-Garcia, J.M.,Grieco, A.,Medina, M.,Boneta, S.,Pey, A.L. (deposition date: 2023-12-13, release date: 2024-05-29)

• Primary citation: Grieco, A.,Boneta, S.,Gavira, J.A.,Pey, A.L.,Basu, S.,Orlans, J.,Sanctis, D.,Medina, M.,Martin-Garcia, J.M.; Structural dynamics and functional cooperativity of human NQO1 by ambient temperature serial crystallography and simulations.; Protein Sci., 33:e4957-e4957, 2024; PubMed: 38501509; DOI: 10.1002/pro.4957

Experimental method

X-RAY DIFFRACTION (2.5 Å)