8RBH
Crystal structure of the kelch domain of human KLHL12 in complex with PEF1 peptide
Summary for 8RBH
Entry DOI | 10.2210/pdb8rbh/pdb |
Descriptor | Kelch-like protein 12, Peflin, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | e3 ligase, protein binding, peptide binding, kelch-like protein, kelch like family member 12., ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 67967.89 |
Authors | Ramdass, A.E.,Chen, Z.,Dalietou, E.V.,Manning, C.E.,Bullock, A.N. (deposition date: 2023-12-04, release date: 2024-12-11) |
Primary citation | Ramdass, A.E.,Dalietou, E.V.,Chen, Z.,Platt, M.,Aitmakhanova, K.,Fedorov, O.,Bullock, A.N. Structural basis for co-adaptor and antagonist binding to the KLHL12 E3 ligase To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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