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8RBH

Crystal structure of the kelch domain of human KLHL12 in complex with PEF1 peptide

Summary for 8RBH
Entry DOI10.2210/pdb8rbh/pdb
DescriptorKelch-like protein 12, Peflin, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordse3 ligase, protein binding, peptide binding, kelch-like protein, kelch like family member 12., ligase
Biological sourceHomo sapiens (human)
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Total number of polymer chains4
Total formula weight67967.89
Authors
Ramdass, A.E.,Chen, Z.,Dalietou, E.V.,Manning, C.E.,Bullock, A.N. (deposition date: 2023-12-04, release date: 2024-12-11)
Primary citationRamdass, A.E.,Dalietou, E.V.,Chen, Z.,Platt, M.,Aitmakhanova, K.,Fedorov, O.,Bullock, A.N.
Structural basis for co-adaptor and antagonist binding to the KLHL12 E3 ligase
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.88 Å)
Structure validation

237735

数据于2025-06-18公开中

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