8R47
AL amyloid fibril from the FOR010 light chain
Summary for 8R47
Entry DOI | 10.2210/pdb8r47/pdb |
EMDB information | 18881 |
Descriptor | lambda 3 immunoglobulin light chain fragment, residues 4-116 (1 entity in total) |
Functional Keywords | amyloid fibril, al amyloid, protein fibril |
Biological source | Homo sapiens |
Total number of polymer chains | 6 |
Total formula weight | 72380.02 |
Authors | Pfeiffer, P.B.,Banerjee, S.,Schmidt, M.,Faendrich, M. (deposition date: 2023-11-13, release date: 2024-06-26) |
Primary citation | Karimi-Farsijani, S.,Pfeiffer, P.B.,Banerjee, S.,Baur, J.,Kuhn, L.,Kupfer, N.,Hegenbart, U.,Schonland, S.O.,Wiese, S.,Haupt, C.,Schmidt, M.,Fandrich, M. Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. Nat Commun, 15:5121-5121, 2024 Cited by PubMed: 38879609DOI: 10.1038/s41467-024-49520-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.25 Å) |
Structure validation
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