8R0V

SARS-CoV-2 Mpro (Omicron, P132H) in complex with alpha-ketoamide 13b-K at pH 6.5

Summary for 8R0V

• Entry DOI: 10.2210/pdb8r0v/pdb
• Descriptor: 3C-like proteinase nsp5, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate (3 entities in total)
• Functional Keywords: sars-cov-2; main protease; omicron; molecular dynamics; pro>his mutant; double mutant, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 4
• Total formula weight: 137849.06

Authors

Ibrahim, M.,Sun, X.,Hilgenfeld, R. (deposition date: 2023-11-01, release date: 2023-11-29)

• Primary citation: Ibrahim, M.,Hilgenfeld, R.,Sun, X.; SARS-CoV-2 Omicron (P132H) complex with alpha-ketoamide 13b-K at pH 6.5; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.48 Å)