8R0I

Pseudomonas aeruginosa FabF C164A in complex with 3-amino-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)benzamide

Summary for 8R0I

• Entry DOI: 10.2210/pdb8r0i/pdb
• Related: 8PD1 8PFZ
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, FORMIC ACID, 3-azanyl-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)benzamide, ... (6 entities in total)
• Functional Keywords: inhibitor, protein-ligand complex, fabf, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 89054.06

Authors

Yadrykhinsky, V.,Brenk, R. (deposition date: 2023-10-31, release date: 2024-03-06, Last modification date: 2024-05-08)

• Primary citation: Jalencas, X.,Berg, H.,Espeland, L.O.,Sreeramulu, S.,Kinnen, F.,Richter, C.,Georgiou, C.,Yadrykhinsky, V.,Specker, E.,Jaudzems, K.,Miletic, T.,Harmel, R.,Gribbon, P.,Schwalbe, H.,Brenk, R.,Jirgensons, A.,Zaliani, A.,Mestres, J.; Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection.; Rsc Med Chem, 15:1176-1188, 2024; PubMed: 38665834; DOI: 10.1039/d3md00724c

Experimental method

X-RAY DIFFRACTION (1.51 Å)