8QY4
Structure of interleukin 11 (gp130 P496L mutant).
Summary for 8QY4
Entry DOI | 10.2210/pdb8qy4/pdb |
EMDB information | 18741 |
Descriptor | Interleukin-11, Interleukin-6 receptor subunit beta, Interleukin-11 receptor subunit alpha, ... (5 entities in total) |
Functional Keywords | interleukin, gp130, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 343338.98 |
Authors | Gardner, S.,Bubeck, D.,Jin, Y. (deposition date: 2023-10-25, release date: 2024-02-21, Last modification date: 2024-09-04) |
Primary citation | Gardner, S.,Jin, Y.,Fyfe, P.K.,Voisin, T.B.,Bellon, J.S.,Pohler, E.,Piehler, J.,Moraga, I.,Bubeck, D. Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. Nat Commun, 15:2071-2071, 2024 Cited by PubMed: 38453915DOI: 10.1038/s41467-024-46235-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.06 Å) |
Structure validation
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