8QWT

Ligninolytic manganese peroxidase Cst-MnP1 from Agaricales mushrooms in complex with a manganese ion

8QWT の概要

• エントリーDOI: 10.2210/pdb8qwt/pdb
• 分子名称: Peroxidase, PROTOPORPHYRIN IX CONTAINING FE, MANGANESE (II) ION, ... (8 entities in total)
• 機能のキーワード: manganese peroxidase, fungal, ligninolytic, oxidoreductase
• 由来する生物種: Cyathus striatus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36106.03

構造登録者

Santillana, E.,Romero, A. (登録日: 2023-10-20, 公開日: 2024-06-26, 最終更新日: 2024-10-23)

主引用文献

Sanchez-Ruiz, M.I.,Santillana, E.,Linde, D.,Romero, A.,Martinez, A.T.,Ruiz-Duenas, F.J.
Structure-function characterization of two enzymes from novel subfamilies of manganese peroxidases secreted by the lignocellulose-degrading Agaricales fungi Agrocybe pediades and Cyathus striatus.
Biotechnol Biofuels Bioprod, 17:74-74, 2024

PubMed Abstract: Manganese peroxidases (MnPs) are, together with lignin peroxidases and versatile peroxidases, key elements of the enzymatic machineries secreted by white-rot fungi to degrade lignin, thus providing access to cellulose and hemicellulose in plant cell walls. A recent genomic analysis of 52 Agaricomycetes species revealed the existence of novel MnP subfamilies differing in the amino-acid residues that constitute the manganese oxidation site. Following this in silico analysis, a comprehensive structure-function study is needed to understand how these enzymes work and contribute to transform the lignin macromolecule.

PubMed: 38824538
DOI: 10.1186/s13068-024-02517-1

実験手法

X-RAY DIFFRACTION (1.5 Å)