8QWS

Crystal structure of CotB2 variant V80L in complex with alendronate

Summary for 8QWS

• Entry DOI: 10.2210/pdb8qws/pdb
• Descriptor: Cyclooctat-9-en-7-ol synthase, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, MAGNESIUM ION, ... (9 entities in total)
• Functional Keywords: terpene synthase, cyclooctatin, lyase
• Biological source: Streptomyces melanosporofaciens
• Total number of polymer chains: 2
• Total formula weight: 75955.78

Authors

Dimos, N.,Himpich, S.,Ringel, M.,Driller, R.,Major, D.T.,Brueck, T.,Loll, B. (deposition date: 2023-10-20, release date: 2024-04-24, Last modification date: 2024-11-06)

• Primary citation: Himpich, S.,Ringel, M.,Schwartz, R.,Dimos, N.,Driller, R.,Helmer, C.P.O.,Kumar Gupta, P.,Haack, M.,Thomas Major, D.,Bruck, T.,Loll, B.; How Can the Diterpene Synthase CotB2V80L Alter the Product Profile?; Chemcatchem, n/a:-, 2024; DOI: 10.1002/cctc.202400711

Experimental method

X-RAY DIFFRACTION (1.6 Å)