8QWF
ReChb - crRNA - target dsDNA complex in the presence of collateral dsDNA
Summary for 8QWF
Entry DOI | 10.2210/pdb8qwf/pdb |
EMDB information | 18691 18692 18693 18694 |
Descriptor | ReChb, crRNA, non target DNA, ... (5 entities in total) |
Functional Keywords | cas, biosynthetic protein, cryo-em, ancestral sequence reconstruction, biotechnology, dna, rna |
Biological source | synthetic construct More |
Total number of polymer chains | 4 |
Total formula weight | 185803.87 |
Authors | Lopez-Alonso, J.P.,Ubarretxena-Belandia, I.,Tascon, I. (deposition date: 2023-10-19, release date: 2024-10-02) |
Primary citation | Jabalera, Y.,Tascon, I.,Samperio, S.,Lopez-Alonso, J.P.,Gonzalez-Lopez, M.,Aransay, A.M.,Abascal-Palacios, G.,Beisel, C.L.,Ubarretxena-Belandia, I.,Jimenez-Perez, R. A resurrected ancestor of Cas12a expands target access and substrate 2 recognition for nucleic-acid editing and detection Nature Biotechnology, 2024 |
Experimental method | ELECTRON MICROSCOPY (3.08 Å) |
Structure validation
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