8QVG
Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound.
Summary for 8QVG
| Entry DOI | 10.2210/pdb8qvg/pdb |
| Descriptor | Bifunctional epoxide hydrolase 2, N-(3,3-DIPHENYLPROPYL)PYRROLIDINE-1-CARBOXAMIDE (3 entities in total) |
| Functional Keywords | inhibitor, serial crystallography, drug discovery, fixed target, room temperature, microcrystals, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 62307.10 |
| Authors | Dunge, A.,Uwangue, O.,Phan, C.,Bjelcic, M.,Gunnarsson, J.,Wehlander, G.,Kack, H.,Branden, G. (deposition date: 2023-10-18, release date: 2024-08-14, Last modification date: 2024-09-11) |
| Primary citation | Dunge, A.,Phan, C.,Uwangue, O.,Bjelcic, M.,Gunnarsson, J.,Wehlander, G.,Kack, H.,Branden, G. Exploring serial crystallography for drug discovery. Iucrj, 11:831-842, 2024 Cited by PubMed: 39072424DOI: 10.1107/S2052252524006134 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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